Antispasmodic drugs and anti-emetics
Trimebutine Maleate 100 mg
20Tablets
T52
361/2006
31/10/2006
Mechanism Of Action | Trimebutine is a noncompetitive spasmolytic agent. It possesses moderate opiate receptor affinity and has a marked antiserotonin activity especially on muscarinic receptors. Trimebutine does not alter normal intestinal motility, but regulates abnormal intestinal activity |
INDICATIONS | Known hypersensitivity to trimebutine or any of the excipients. |
Side EFFECTS | : The commonly reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations and headaches. Rash, menstrual problems, painful enlargement of breasts, anxiety, urine retention and slight deafness were also infrequently reported. |
DRUG INTERACTIONS | Trimebutine increases the duration of d-tubocurarine-induced cuarization. |
Pregnancy And lactations | The use of trimebutine in pregnant women is not recommended. TRIMELON is not recommended for use in children under 12 years of age. |
Dosage And Administration | The adult recommended dose is up to 600 mg daily in divided doses. It may be administered as 1-2 tablets three times daily before meals |
Storage Conditions | Store below 30 ْ c . in a dry place. Keep out of reach of children. |