No steroidal Anti-inflammatory drugs
Meloxicam 15 mg
20Tablets
T23
105/2003
4/6/2003
Mechanism Of Action | Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities. The mechanism of action like that of other NSAIDS may be related to prostaglandin synthetase inhibition. Meloxicam is a Cyclo-oxygenase-2 (COX-2) inhibitor with a 75-fold selectivity for COX-2 relative to COX-1 in recombinant human enzymes. |
INDICATIONS | Romacalm is used in the management of rheumatoid arthritis, for the short-term symptomatic treatment of acute exacerbation of osteoarthritis, and for the symptomatic treatment of ankylosing spondylitis. |
CONTRAINDICATIONS | Romacalm is contraindicated in patients with hypersensitivity to drug, and in those with history of asthma or allergic-type reactions after taking aspirin or other NSAIDs. |
Side EFFECTS | The most frequently reported side effects include headache, fatigue, dizziness, diarrhea, stomach pain, colitis, nausea, and upper respiratory tract infection. |
WARNINGS | Romacalm should be avoided in patients with renal failure, unless receiving dialysis, in severe hepatic failure, and in bleeding disorders. |
DRUG INTERACTIONS | Meloxicam may cause elevations in liver tests. It may also cause elevated blood creatinine levels. |
Pregnancy And lactations | Romacalm is also contraindicated during pregnancy and lactation. |
Dosage And Administration | -For the treatment of rheumatoid arthritis: one tablet of Romacalm -15 daily. -For the treatment of osteoarthritis: one tablet of Romacalm -7.5 daily, increased if necessary to one tablet of Romacalm --15 daily. |
OVERDOSE | It has been shown that cholestyramine accelerates Meloxicam elimination, therefore it may be used in case of overdose |
Storage Conditions | Store below 30ْ C |