Anti viral agent
Aciclovir 5 g /100g
2g/Tube - 5g/Tube
CR-12
41/2011
9/2/2011
Mechanism Of Action | Kana-Zovak(Cream) contains the active ingredient Acyclovir, which is an antiviral medicine. Acyclovir works by stopping the herpes simplex virus from reproducing and infecting more cells. Acyclovir is converted to a more active form inside cells of the body that are infected with herpes simplex. The activated Acyclovir then works by blocking the action of a viral enzyme called DNA polymerase. The herpes virus needs the DNA polymerase enzyme to copy its genetic material from RNA to DNA. This process is necessary for the virus to multiply and continue to survive. By blocking the action of DNA polymerase, Acyclovir prevents the herpes virus from multiplying. This controls the infection and helps the immune system to deal with it. |
INDICATIONS | Kana-Zovak(Cream) is indicated for the treatment of is indicated for the treatment of recurrent herpes labialis (cold sores ) in adults and adolescents (12 years of age and older). |
CONTRAINDICATIONS | Kana-Zovak(Cream) is contraindicated in patients with known hypersensitivity to Acyclovir, valacyclovir, or any component of the formulation. |
Side EFFECTS | Allergic inflammation of the skin (Contact dermatitis) , stinging or burning at the area of application, itching at the area application drying of skin in area of use , flushing of the skin due to widening of the small blood vessels ( erythema). |
WARNINGS | Kana-Zovak(Cream) is intended for cutaneous use only and should not be used in the eye or inside the mouth or nose . Kana-Zovak(Cream) should only be used on herpes labialis on the affected external aspects of the lips and face . Kana-Zovak(Cream)is not recommended in immunocomproised patients. |
DRUG INTERACTIONS | Coadministration of probenecid with acyclovir may increase the mean acyclovir half-life and the area under the concentration-time curve. Urinary excretion and renal clearance were correspondingly reduced. |
Pregnancy And lactations | Zovak(Cream)should be used with caution during pregnancy and breast –feeding. |
Dosage And Administration | Kana-Zovak (Cream) should be applied 5 times per day for 4 days .therapy should be initiated as early as possible following onset of signs and symptoms |
Storage Conditions | Store below 30°C. For external use only Keep out of reach of children. Do not use in eyes. Prescription only medicine. |