• Chemical Composition

    Fexofenadine HCL 120 mg /1 tab

  • Packing

    20Coated Tablets

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Mechanism Of Action : Fexofenadine, a metabolite of terfenadine, is an antihistamine with selective peripheral H1-receptor antagonist activity. It has no sedative or other central nervous system effects, because fexofenadine does not cross the blood-brain barrier.
INDICATIONS ALLEGRADINE (Fexofenadine HCl) is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 12 years of age and older. Like other nonsedating H1 receptor antagonists such as loratidine and cetirizine, fexofenadine reduces sneezing, rhinorrhoea, itchy nose, palate or throat, and itchy, watery, red eyes. Once daily fexofenadine reduced the symptoms of chronic idiopathic urticaria for up to 6 weeks.
CONTRAINDICATIONS : ALLEGRADINE is contraindicated in patients with known hypersensitivity to Fexofenadine HCl
Side EFFECTS Adverse events occurring in less than 1% of fexofenadine HCl-treated patients (60 mg twice daily) include viral Infection (cold, flu), nausea, dysmenorrhea, drowsiness, dyspepsia, and fatigue.
DRUG INTERACTIONS Antacids (aluminium and magnesium hydroxide) may reduce the absorption of Fexofenadine. Drug \ Clinical Laboratory Test Interactions: None encountered
Pregnancy And lactations ALLEGRADINE should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when ALLEGRADINE is administered to a nursing mother.
Dosage And Administration -Adults and children aged 12 years and over: The recommended dose of ALLEGRADINE is one tablet (60 mg) twice daily (morning and evening). Seasonal Allergic Rhinitis Adults and Children aged 12 years or older:The recommended dose is 60 mg, as required up to a maximum of one tablet twice daily, or 120 mg once daily, or 180 mg once daily for adults and children over 12 years of age. Chronic Idiopathic Urticaria Adults and children aged 12 years and over: The recommended dose is 180 mg once daily for adults and children aged 12 years and over
OVERDOSE : Single doses of fexofenadine HCl up to 800 mg, and doses up to 690 mg twice daily for one month were administered without the development of clinically significant adverse events. In the event of overdose, consider standard measures to remove any unabsorbed drug. Symptomatic and supportive treatment is recommended.
Storage Conditions “Keep out of reach of children” “Store below 30 C”