the name
Acnemycin
Lotion symbol
E.L-03
Pharmaceutical form
External solutions
License number and date
200/2005
20/04/2005
Indication
Anti-infective and antibacterial medications
Anti-infective & antibacterial drugs
Shelf life
3 year
Quantity
25 ml
Installation
all 1 One ml of acnimycin topical solution contains clindamycin phosphate 11,85 mg equivalent to 10 mg of clindamycin base
Excipients
Distilled water, isopropyl alcohol, propylene glycol
Pharmacological properties and mechanism of action:
Clindamycin phosphate is an antibiotic used to treat acne. It can also be used to treat other skin conditions. It can be used alone or in combination.
With one or more other medicines )Dermal or oral( To treat acne.
Clindamycin can inhibit the growth of bacteria or kill them, depending on the concentration of the drug used in the area of infection, as well as the sensitivity of the infected bacteria.
For him, clindamycin esters are considered )Balmitate, hydrochloride and phosphate( Ineffective in glass, but becomes effective after rapid hydration in organic matter.
The basis for the release of clindamycin is that clindamycin inhibits protein synthesis in sensitive bacteria after binding to the ribosomal subunit S. 50 , where
Its primary effect is to inhibit peptide bond formation.
Pharmacokinetics:
Indications:
Acnimycin topical solution is used to treat mild to moderate cases of acne, as clindamycin helps reduce the number of bacteria.
It causes acne vulgaris and is also used as an anti-inflammatory.
Contraindications:
Acnimycin topical solution should not be used in patients with a history of hypersensitivity to clindamycin or lincomycin.
Pregnancy and breastfeeding:
The safety of use during pregnancy and breastfeeding has also not been proven, so it should be used during pregnancy only when absolutely necessary, and breastfeeding should be stopped during treatment with the preparation..
Driving and using machines:
Warnings and precautions:
The use of dermatological preparations of clindamycin can result in systemic absorption of the antibiotic from the skin surface, which has been reported to occur.
Cases of diarrhea, bloody diarrhea, and colitis )Including pseudomembranous colitis( When using clindamycin systemically and topically.
Acnimycin topical solution contains in its excipients a large percentage of alcohol, which can cause burns and eye irritation in the event of contact with the solution.
With sensitive surfaces )Eyes, scratched skin, mucous membranes( Wash with large amounts of cold water.
The solution has an unpleasant taste, so caution should be taken when applying it to areas around the mouth, and acnimycin should be used with caution in patients with fever.
Hay, asthma and eczema. Caution should also be exercised when using the preparation in patients with a history of regional enteritis or colitis.
Ulcerative colitis or a history of colitis associated with the use of antibiotics.
If there is no improvement in acne vulgaris or acne within 6 Weeks or if the condition worsens, you should consult a specialist doctor. Except that
Treatment can continue for a period of time 8- 12 A week before noticing complete improvement. Safety and effectiveness of using the preparation in children under the age of 12 Not installed
Explicitly
Drug interactions:
It has been observed that there is an antagonism between clindamycin and erythromycin in vitro, so it is preferable not to use the two drugs at the same time clinically..
Side effects
The most common side effects can include burning, itching, peeling of the skin, redness and dryness of the skin.
– Rare and less common side effects include abdominal pain, diarrhea, colitis, oily skin, skin inflammation and irritation, and gastrointestinal disorders..
Dosage and method of use:
It has been observed that there is an antagonism between clindamycin and erythromycin in vitro, so it is preferable not to use the two drugs at the same time clinically..
Overdose:
Topically applied clindamycin can be absorbed in sufficient amounts to produce systemic effects. If a case of overdose is suspected, you must immediately resort to the nearest medical center.
Packing:
Glass bottle containing 25 ml of acnimycin topical solution.
Preservation and storage conditions:
Store at a temperature below 30 °C, protect from light, keep out of reach of children.
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